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Xanthan Gum–Konjac Glucomannan Blend Hydrogel for Wound Healing
Hydrogels are considered to be the most ideal materials for the production of wound dressings since they display a three-dimensional structure that mimics the native extracellular matrix of skin as well as a high-water content, which confers a moist environment at the wound site. Until now, differen...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023620/ https://www.ncbi.nlm.nih.gov/pubmed/31947937 http://dx.doi.org/10.3390/polym12010099 |
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author | Alves, Andreia Miguel, Sónia P. Araujo, André R.T.S. de Jesús Valle, María José Sánchez Navarro, Amparo Correia, Ilídio J. Ribeiro, Maximiano P. Coutinho, Paula |
author_facet | Alves, Andreia Miguel, Sónia P. Araujo, André R.T.S. de Jesús Valle, María José Sánchez Navarro, Amparo Correia, Ilídio J. Ribeiro, Maximiano P. Coutinho, Paula |
author_sort | Alves, Andreia |
collection | PubMed |
description | Hydrogels are considered to be the most ideal materials for the production of wound dressings since they display a three-dimensional structure that mimics the native extracellular matrix of skin as well as a high-water content, which confers a moist environment at the wound site. Until now, different polymers have been used, alone or blended, for the production of hydrogels aimed for this biomedical application. From the best of our knowledge, the application of a xanthan gum–konjac glucomannan blend has not been used for the production of wound dressings. Herein, a thermo-reversible hydrogel composed of xanthan gum–konjac glucomannan (at different concentrations (1% and 2% w/v) and ratios (50/50 and 60/40)) was produced and characterized. The obtained data emphasize the excellent physicochemical and biological properties of the produced hydrogels, which are suitable for their future application as wound dressings. |
format | Online Article Text |
id | pubmed-7023620 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70236202020-03-11 Xanthan Gum–Konjac Glucomannan Blend Hydrogel for Wound Healing Alves, Andreia Miguel, Sónia P. Araujo, André R.T.S. de Jesús Valle, María José Sánchez Navarro, Amparo Correia, Ilídio J. Ribeiro, Maximiano P. Coutinho, Paula Polymers (Basel) Article Hydrogels are considered to be the most ideal materials for the production of wound dressings since they display a three-dimensional structure that mimics the native extracellular matrix of skin as well as a high-water content, which confers a moist environment at the wound site. Until now, different polymers have been used, alone or blended, for the production of hydrogels aimed for this biomedical application. From the best of our knowledge, the application of a xanthan gum–konjac glucomannan blend has not been used for the production of wound dressings. Herein, a thermo-reversible hydrogel composed of xanthan gum–konjac glucomannan (at different concentrations (1% and 2% w/v) and ratios (50/50 and 60/40)) was produced and characterized. The obtained data emphasize the excellent physicochemical and biological properties of the produced hydrogels, which are suitable for their future application as wound dressings. MDPI 2020-01-04 /pmc/articles/PMC7023620/ /pubmed/31947937 http://dx.doi.org/10.3390/polym12010099 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Alves, Andreia Miguel, Sónia P. Araujo, André R.T.S. de Jesús Valle, María José Sánchez Navarro, Amparo Correia, Ilídio J. Ribeiro, Maximiano P. Coutinho, Paula Xanthan Gum–Konjac Glucomannan Blend Hydrogel for Wound Healing |
title | Xanthan Gum–Konjac Glucomannan Blend Hydrogel for Wound Healing |
title_full | Xanthan Gum–Konjac Glucomannan Blend Hydrogel for Wound Healing |
title_fullStr | Xanthan Gum–Konjac Glucomannan Blend Hydrogel for Wound Healing |
title_full_unstemmed | Xanthan Gum–Konjac Glucomannan Blend Hydrogel for Wound Healing |
title_short | Xanthan Gum–Konjac Glucomannan Blend Hydrogel for Wound Healing |
title_sort | xanthan gum–konjac glucomannan blend hydrogel for wound healing |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023620/ https://www.ncbi.nlm.nih.gov/pubmed/31947937 http://dx.doi.org/10.3390/polym12010099 |
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