Development of Novel Galactosylated PLGA Nanoparticles for Hepatocyte Targeting Using Molecular Modelling

Doxorubicin-loaded PLGA nanoparticles conjugated with a new galactose-based ligand for the specific recognition by human hepatoma cellular carcinoma cells (Hep G2) were successfully produced. The new targeting compound was selected using molecular docking combined with quantum chemical calculations...

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Detalles Bibliográficos
Autores principales: Raposo, Cláudia D., Costa, Rita, Petrova, Krasimira T., Brito, Catarina, Scotti, Marcus T., Cardoso, M. Margarida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023654/
https://www.ncbi.nlm.nih.gov/pubmed/31947904
http://dx.doi.org/10.3390/polym12010094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023654/
https://www.ncbi.nlm.nih.gov/pubmed/31947904
http://dx.doi.org/10.3390/polym12010094

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