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The CYP2C192 and CYP2C1917 Polymorphisms Influence Responses to Clozapine for the Treatment of Schizophrenia

INTRODUCTION: Clozapine (CLZ) is the gold standard drug for treatment-refractory schizophrenia (TRS). However, approximately 30% of patients partially respond to CLZ, defining this subset with super refractory schizophrenia (SRS). Alterations in enzyme activity may affect CLZ responses; the CYP3A4,...

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Detalles Bibliográficos
Autores principales:	Rodrigues-Silva, Christielly, Semedo, Agostinho Tavares, Neri, Hiasmin Franciely da Silva, Vianello, Rosana Pereira, Galaviz-Hernández, Carlos, Sosa-Macías, Martha, de Brito, Rodrigo Bernini, Ghedini, Paulo César
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023876/ https://www.ncbi.nlm.nih.gov/pubmed/32103962 http://dx.doi.org/10.2147/NDT.S228103

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