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The Application of Reversible Intramolecular Sulfonamide Ligation to Modulate Reactivity in Organometallic Ruthenium(II) Diamine Complexes

Metallation of biomacromolecular species forms the basis for the anticancer activity of many metallodrugs. A major limitation of these compounds is that their reactivity is indiscriminate and can, in principle, occur in healthy tissue as well as cancerous tissue, potentially leading to side effects...

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Detalles Bibliográficos
Autores principales: Kemp, Samuel A., Prior, Timothy J., Savoie, Huguette, Boyle, Ross W., Murray, Benjamin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024221/
https://www.ncbi.nlm.nih.gov/pubmed/31936104
http://dx.doi.org/10.3390/molecules25020244