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The Application of Reversible Intramolecular Sulfonamide Ligation to Modulate Reactivity in Organometallic Ruthenium(II) Diamine Complexes
Metallation of biomacromolecular species forms the basis for the anticancer activity of many metallodrugs. A major limitation of these compounds is that their reactivity is indiscriminate and can, in principle, occur in healthy tissue as well as cancerous tissue, potentially leading to side effects...
Autores principales: | Kemp, Samuel A., Prior, Timothy J., Savoie, Huguette, Boyle, Ross W., Murray, Benjamin S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024221/ https://www.ncbi.nlm.nih.gov/pubmed/31936104 http://dx.doi.org/10.3390/molecules25020244 |
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