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Immunomodulatory Drugs Alter the Metabolism and the Extracellular Release of Soluble Mediators by Normal Monocytes

Immunomodulatory drugs (IMiDs) are used in the treatment of hematological malignancies, especially multiple myeloma. IMiDs have direct anticancer effects but also indirect effects via cancer-supporting stromal cells. Monocytes are a stromal cell subset whose metabolism is modulated by the microenvir...

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Detalles Bibliográficos
Autores principales: Rundgren, Ida Marie, Ryningen, Anita, Anderson Tvedt, Tor Henrik, Bruserud, Øystein, Ersvær, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024334/
https://www.ncbi.nlm.nih.gov/pubmed/31963193
http://dx.doi.org/10.3390/molecules25020367