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Immunomodulatory Drugs Alter the Metabolism and the Extracellular Release of Soluble Mediators by Normal Monocytes
Immunomodulatory drugs (IMiDs) are used in the treatment of hematological malignancies, especially multiple myeloma. IMiDs have direct anticancer effects but also indirect effects via cancer-supporting stromal cells. Monocytes are a stromal cell subset whose metabolism is modulated by the microenvir...
Autores principales: | Rundgren, Ida Marie, Ryningen, Anita, Anderson Tvedt, Tor Henrik, Bruserud, Øystein, Ersvær, Elisabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024334/ https://www.ncbi.nlm.nih.gov/pubmed/31963193 http://dx.doi.org/10.3390/molecules25020367 |
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