Tomatidine Represses Invasion and Migration of Human Osteosarcoma U2OS and HOS Cells by Suppression of Presenilin 1 and c-Raf–MEK–ERK Pathway

Osteosarcoma, which is the most prevalent malignant bone tumor, is responsible for the great majority of bone cancer-associated deaths because of its highly metastatic potential. Although tomatidine is suggested to serve as a chemosensitizer in multidrug-resistant tumors, the anti-metastatic effect...

Descripción completa

Detalles Bibliográficos
Autores principales: Hsieh, Min-Hong, Yang, Jia-Sin, Lin, Renn-Chia, Hsieh, Yi-Hsien, Yang, Shun-Fa, Chang, Horng-Rong, Lu, Ko-Hsiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024336/
https://www.ncbi.nlm.nih.gov/pubmed/31941156
http://dx.doi.org/10.3390/molecules25020326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024336/
https://www.ncbi.nlm.nih.gov/pubmed/31941156
http://dx.doi.org/10.3390/molecules25020326

Ejemplares similares