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Tomatidine Represses Invasion and Migration of Human Osteosarcoma U2OS and HOS Cells by Suppression of Presenilin 1 and c-Raf–MEK–ERK Pathway

Osteosarcoma, which is the most prevalent malignant bone tumor, is responsible for the great majority of bone cancer-associated deaths because of its highly metastatic potential. Although tomatidine is suggested to serve as a chemosensitizer in multidrug-resistant tumors, the anti-metastatic effect...

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Detalles Bibliográficos
Autores principales:	Hsieh, Min-Hong, Yang, Jia-Sin, Lin, Renn-Chia, Hsieh, Yi-Hsien, Yang, Shun-Fa, Chang, Horng-Rong, Lu, Ko-Hsiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024336/ https://www.ncbi.nlm.nih.gov/pubmed/31941156 http://dx.doi.org/10.3390/molecules25020326

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