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Allosteric Cannabinoid Receptor 1 (CB1) Ligands Reduce Ocular Pain and Inflammation
Cannabinoid receptor 1 (CB1) activation has been reported to reduce transient receptor potential cation channel subfamily V member 1 (TRPV1)-induced inflammatory responses and is anti-nociceptive and anti-inflammatory in corneal injury. We examined whether allosteric ligands, can modulate CB1 signal...
Autores principales: | Thapa, Dinesh, Cairns, Elizabeth A., Szczesniak, Anna-Maria, Kulkarni, Pushkar M., Straiker, Alex J., Thakur, Ganesh A., Kelly, Melanie E. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024337/ https://www.ncbi.nlm.nih.gov/pubmed/31968549 http://dx.doi.org/10.3390/molecules25020417 |
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