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Synthesis of Elaborate Benzofuran-2-Carboxamide Derivatives through a Combination of 8-Aminoquinoline Directed C–H Arylation and Transamidation Chemistry

Herein, we present a short and highly modular synthetic route that involves 8-aminoquinoline directed C–H arylation and transamidation chemistry, and which enables access to a wide range of elaborate benzofuran-2-carboxamides. For the directed C–H arylation reactions, Pd catalysis was used to instal...

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Detalles Bibliográficos
Autores principales: Oschmann, Michael, Johansson Holm, Linus, Pourghasemi-Lati, Monireh, Verho, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024369/
https://www.ncbi.nlm.nih.gov/pubmed/31952313
http://dx.doi.org/10.3390/molecules25020361