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Computational determination of human PPARG gene: SNPs and prediction of their effect on protein functions of diabetic patients
BACKGROUND: The Peroxisome proliferator-activated receptor gamma gene (PPARG), encodes a member of the peroxisome-activated receptor subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) which regulate transcription of various genes. Three subtypes of PPARs are kno...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024687/ https://www.ncbi.nlm.nih.gov/pubmed/32064572 http://dx.doi.org/10.1186/s40169-020-0258-1 |