Computational determination of human PPARG gene: SNPs and prediction of their effect on protein functions of diabetic patients

BACKGROUND: The Peroxisome proliferator-activated receptor gamma gene (PPARG), encodes a member of the peroxisome-activated receptor subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) which regulate transcription of various genes. Three subtypes of PPARs are kno...

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Detalles Bibliográficos
Autores principales: Mustafa, Howeida Abdullah, Albkrye, Afraa Mohamed Suliman, AbdAlla, Buthiena Mohamed, Khair, Mona AbdelRahman Mohammed, Abdelwahid, Nidal, Elnasri, Hind Abdelaziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024687/
https://www.ncbi.nlm.nih.gov/pubmed/32064572
http://dx.doi.org/10.1186/s40169-020-0258-1

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