N-Methyl-D-Aspartate Antagonists and Steroids for the Prevention of Persisting Post-Surgical Pain After Thoracoscopic Surgeries: A Randomized Controlled, Factorial Design, International, Multicenter Pilot Trial

PURPOSE: We conducted a feasibility 2×2 factorial trial comparing N-methyl-D-aspartate (NMDA) antagonists (intravenous ketamine and oral memantine) versus placebo and intravenous steroids versus placebo, in patients having elective video-assisted thoracic surgery lobectomies, at St. Joseph’s Hamilto...

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Detalles Bibliográficos
Autores principales: Shanthanna, Harsha, Turan, Alparslan, Vincent, Jessica, Saab, Remie, Shargall, Yaron, O’Hare, Turlough, Davis, Kimberly, Fonguh, Sylvanus, Balasubramaniam, Kumar, Paul, James, Gilron, Ian, Kehlet, Henrik, Sessler, Daniel I, Bhandari, Mohit, Thabane, Lehana, Devereaux, PJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024793/
https://www.ncbi.nlm.nih.gov/pubmed/32104059
http://dx.doi.org/10.2147/JPR.S237058

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