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New intranasal cross-linked mosapride xyloglucan pluronics micelles (MOS-XPMs) for reflux esophagitis disease: In-vitro optimization and improved therapeutic efficacy

Mosapride belongs to class IV in Biopharmaceutics Classification System and is used in the treatment of reflux esophagitis. It exhibits poor bioavailability due to limited permeability, solubility and extensive first-pass metabolism. In this study, intranasal mosapride-loaded cross-linked xyloglucan...

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Detalles Bibliográficos
Autores principales:	Hammad, Reham Waheed, Sanad, Rania Abdel-Basset, Abdelmalak, Nevine Shawky, Torad, Faisal A., Latif, Randa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025289/ https://www.ncbi.nlm.nih.gov/pubmed/32089877 http://dx.doi.org/10.1016/j.jare.2020.01.013

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