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Clemastine Fumarate Protects Against Myocardial Ischemia Reperfusion Injury by Activating the TLR4/PI3K/Akt Signaling Pathway

Our pilot studies have shown that clemastine fumarate (CLE) can protect against myocardial ischemia-reperfusion injury (MIRI) through regulation of toll like receptor 4 (TLR4). However, the protective mechanism of CLE and related signaling pathways for MIRI remains unclear. The objective of this stu...

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Detalles Bibliográficos
Autores principales:	Yuan, Xiaoxiao, Juan, Zhaodong, Zhang, Rui, Sun, Xiaotong, Yan, Ru, Yue, Feng, Huang, Yaru, Yu, Jiacheng, Xia, Xiaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025565/ https://www.ncbi.nlm.nih.gov/pubmed/32116705 http://dx.doi.org/10.3389/fphar.2020.00028

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