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H3K9 Demethylation-Induced R-Loop Accumulation Is Linked to Disorganized Nucleoli

The nucleolar structure and integrity are important for a range of cellular functions of the nucleoli. It has been shown that cells lacking histone H3 Lysine 9 (H3K9) methylation form fragmented nucleoli. However, the molecular mechanism involved remains poorly understood. Here, we present evidence...

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Detalles Bibliográficos
Autores principales: Zhou, Hong, Li, Le, Wang, Qing, Hu, Yan, Zhao, Weiwei, Gautam, Mayank, Li, Lijia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025566/
https://www.ncbi.nlm.nih.gov/pubmed/32117455
http://dx.doi.org/10.3389/fgene.2020.00043

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