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Transcriptome reprogramming and myeloid skewing in haematopoietic stem and progenitor cells in systemic lupus erythematosus

OBJECTIVES: Haematopoietic stem and progenitor cells (HSPCs) are multipotent cells giving rise to both myeloid and lymphoid cell lineages. We reasoned that the aberrancies of immune cells in systemic lupus erythematosus (SLE) could be traced back to HSPCs. METHODS: A global gene expression map of bo...

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Detalles Bibliográficos
Autores principales: Grigoriou, Maria, Banos, Aggelos, Filia, Anastasia, Pavlidis, Pavlos, Giannouli, Stavroula, Karali, Vassiliki, Nikolopoulos, Dionysis, Pieta, Antigone, Bertsias, George, Verginis, Panayotis, Mitroulis, Ioannis, Boumpas, Dimitrios T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025734/
https://www.ncbi.nlm.nih.gov/pubmed/31780527
http://dx.doi.org/10.1136/annrheumdis-2019-215782

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