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Neonatal-derived IL-17 producing dermal γδ T cells are required to prevent spontaneous atopic dermatitis
Atopic Dermatitis (AD) is a T cell-mediated chronic skin disease and is associated with altered skin barrier integrity. Infants with mutations in genes involved in tissue barrier fitness are predisposed towards inflammatory diseases, but most do not develop or sustain the diseases, suggesting that t...
Autores principales: | Spidale, Nicholas A, Malhotra, Nidhi, Frascoli, Michela, Sylvia, Katelyn, Miu, Bing, Freeman, Coral, Stadinski, Brian D, Huseby, Eric, Kang, Joonsoo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025821/ https://www.ncbi.nlm.nih.gov/pubmed/32065580 http://dx.doi.org/10.7554/eLife.51188 |
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