Cargando…

Tgfβ signaling is critical for maintenance of the tendon cell fate

Studies of cell fate focus on specification, but little is known about maintenance of the differentiated state. In this study, we find that the mouse tendon cell fate requires continuous maintenance in vivo and identify an essential role for TGFβ signaling in maintenance of the tendon cell fate. To...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tan, Guak-Kim, Pryce, Brian A, Stabio, Anna, Brigande, John V, Wang, ChaoJie, Xia, Zheng, Tufa, Sara F, Keene, Douglas R, Schweitzer, Ronen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025861/ https://www.ncbi.nlm.nih.gov/pubmed/31961320 http://dx.doi.org/10.7554/eLife.52695

Ejemplares similares

Cell autonomous TGFβ signaling is essential for stem/progenitor cell recruitment into degenerative tendons
por: Tan, Guak-Kim, et al.
Publicado: (2021)

mTORC1 Signaling is a Critical Regulator of Postnatal Tendon Development
por: Lim, Joohyun, et al.
Publicado: (2017)

Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway
por: Blum, Barak, et al.
Publicado: (2014)

How muscle contraction strengthens tendons
por: Glenn, Nicole O, et al.
Publicado: (2019)

Comparison of Tendon Development Versus Tendon Healing and Regeneration
por: He, Peiwen, et al.
Publicado: (2022)

Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate
por: Tang, Wanbo, et al.
Publicado: (2021)

Histone Modifications and Chondrocyte Fate: Regulation and Therapeutic Implications
por: Wan, Chao, et al.
Publicado: (2021)

Arl15 upregulates the TGFβ family signaling by promoting the assembly of the Smad-complex
por: Shi, Meng, et al.
Publicado: (2022)

Tendon Stem/Progenitor Cell Subpopulations and Their Implications in Tendon Biology
por: Huang, Zizhan, et al.
Publicado: (2021)

Mitochondria reorganization upon proliferation arrest predicts individual yeast cell fate
por: Laporte, Damien, et al.
Publicado: (2018)

ATR expands embryonic stem cell fate potential in response to replication stress
por: Atashpaz, Sina, et al.
Publicado: (2020)

Dynamics of primitive streak regression controls the fate of neuromesodermal progenitors in the chicken embryo
por: Guillot, Charlene, et al.
Publicado: (2021)

Tendon-Specific Dicer Deficient Mice Exhibit Hypoplastic Tendon Through the Downregulation of Tendon-Related Genes and MicroRNAs
por: Omoto, Takenori, et al.
Publicado: (2022)

Discrete spatial organization of TGFβ receptors couples receptor multimerization and signaling to cellular tension
por: Rys, Joanna P, et al.
Publicado: (2015)

Starvation-induced regulation of carbohydrate transport at the blood–brain barrier is TGF-β-signaling dependent
por: Hertenstein, Helen, et al.
Publicado: (2021)

Regulation of B cell fate by chronic activity of the IgE B cell receptor
por: Yang, Zhiyong, et al.
Publicado: (2016)

microRNA-mediated regulation of microRNA machinery controls cell fate decisions
por: Liu, Qiuying, et al.
Publicado: (2021)

Transiently heritable fates and quorum sensing drive early IFN-I response dynamics
por: Van Eyndhoven, Laura C, et al.
Publicado: (2023)

Tgfβ signaling is required for tenocyte recruitment and functional neonatal tendon regeneration
por: Kaji, Deepak A, et al.
Publicado: (2020)

The Roles of TGF-β Signaling in Cerebrovascular Diseases
por: Zhang, Yizhe, et al.
Publicado: (2020)

Diverse Role of TGF-β in Kidney Disease
por: Gu, Yue-Yu, et al.
Publicado: (2020)

TGF-β Signaling and Resistance to Cancer Therapy
por: Zhang, Maoduo, et al.
Publicado: (2021)

Editorial: TGF-β and BMP signaling in cancer
por: Yan, Xiaohua, et al.
Publicado: (2022)

EGR4 is critical for cell-fate determination and phenotypic maintenance of geniculate ganglion neurons underlying sweet and umami taste
por: Dutta Banik, Debarghya, et al.
Publicado: (2023)

Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates
por: Basch, Martin L, et al.
Publicado: (2016)

Mitophagy, Mitochondrial Homeostasis, and Cell Fate
por: Ma, Kaili, et al.
Publicado: (2020)

Developmental Perspectives on Arterial Fate Specification
por: Chen, Dongying, et al.
Publicado: (2021)

Editorial: Mitochondrial control of cell fate
por: Gong, Guohua, et al.
Publicado: (2023)

Novel Model of Tendon Regeneration Reveals Distinct Cell Mechanisms Underlying Regenerative and Fibrotic Tendon Healing
por: Howell, Kristen, et al.
Publicado: (2017)

Hyaluronic acid ameliorates the proliferative ability of human amniotic epithelial cells through activation of TGF-β/BMP signaling
por: Tian, Ya-Bing, et al.
Publicado: (2020)

Cytokine receptor-Eb1 interaction couples cell polarity and fate during asymmetric cell division
por: Chen, Cuie, et al.
Publicado: (2018)

AGS3 antagonizes LGN to balance oriented cell divisions and cell fate choices in mammalian epidermis
por: Descovich, Carlos P, et al.
Publicado: (2023)

Editorial: TGF-β in Human Disease: Friend or Foe?
por: Zheng, Guoping, et al.
Publicado: (2021)

The Interplay Between TGF-β Signaling and Cell Metabolism
por: Liu, Huidong, et al.
Publicado: (2022)

Mechanical force regulates tendon extracellular matrix organization and tenocyte morphogenesis through TGFbeta signaling
por: Subramanian, Arul, et al.
Publicado: (2018)

Imaging the fate of histone Cse4 reveals de novo replacement in S phase and subsequent stable residence at centromeres
por: Wisniewski, Jan, et al.
Publicado: (2014)

Polo-like kinase acts as a molecular timer that safeguards the asymmetric fate of spindle microtubule-organizing centers
por: Matellán, Laura, et al.
Publicado: (2020)

Mitochondrial Function in Muscle Stem Cell Fates
por: Bhattacharya, Debasmita, et al.
Publicado: (2020)

Editorial: Chromatin Regulation in Cell Fate Decisions
por: Brumbaugh, Justin, et al.
Publicado: (2021)

Editorial: DNA Replication Stress and Cell Fate
por: Deng, Lin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_39ksuuaeri6k3nreer2v9ol0cu