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Cyclophilin D Contributes to Anesthesia Neurotoxicity in the Developing Brain

Anesthetic sevoflurane induces mitochondrial dysfunction, impairment of neurogenesis, and cognitive impairment in young mice, but the underlying mechanism remains to be determined. Cyclophilin D (CypD) is a modulatory factor for the mitochondrial permeability transition pore (mPTP). We, therefore, s...

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Detalles Bibliográficos
Autores principales:	Zhang, Yiying, Lu, Pan, Liang, Feng, Liufu, Ning, Dong, Yuanlin, Zheng, Jialin Charles, Xie, Zhongcong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026027/ https://www.ncbi.nlm.nih.gov/pubmed/32117955 http://dx.doi.org/10.3389/fcell.2019.00396

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