Analysis of TET2 and EZH2 gene functions in chromosome instability in acute myeloid leukemia

TET2 and EZH2 play important roles in the epigenetic regulation in many cancers. However, their specific roles in acute myeloid leukemia (AML) pathogenesis remain unknown. Here, the expression, methylation or mutation of EZH2 and TET2 was determined and further correlated with the levels of the chro...

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Detalles Bibliográficos
Autores principales: Wang, Jingyi, He, Na, Wang, Ruiqing, Tian, Tian, Han, Fengjiao, Zhong, Chaoqin, Zhang, Chen, Hua, Mingqiang, Ji, Chunyan, Ma, Daoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026035/
https://www.ncbi.nlm.nih.gov/pubmed/32066746
http://dx.doi.org/10.1038/s41598-020-59365-w

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