Comprehensive analysis of a novel mouse model of the 22q11.2 deletion syndrome: a model with the most common 3.0-Mb deletion at the human 22q11.2 locus

The 22q11.2 deletion syndrome (22q11.2DS) is associated with an increased risk for psychiatric disorders. Although most of the 22q11.2DS patients have a 3.0-Mb deletion, existing mouse models only mimic a minor mutation of 22q11.2DS, a 1.5-Mb deletion. The role of the genes existing outside the 1.5-...

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Detalles Bibliográficos
Autores principales: Saito, Ryo, Koebis, Michinori, Nagai, Taku, Shimizu, Kimiko, Liao, Jingzhu, Wulaer, Bolati, Sugaya, Yuki, Nagahama, Kenichiro, Uesaka, Naofumi, Kushima, Itaru, Mori, Daisuke, Maruyama, Kazuaki, Nakao, Kazuki, Kurihara, Hiroki, Yamada, Kiyofumi, Kano, Masanobu, Fukada, Yoshitaka, Ozaki, Norio, Aiba, Atsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026107/
https://www.ncbi.nlm.nih.gov/pubmed/32066675
http://dx.doi.org/10.1038/s41398-020-0723-z

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