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Expression of tert Prevents ALT in Zebrafish Brain Tumors

The activation of a telomere maintenance mechanism (TMM) is an essential step in cancer progression to escape replicative senescence and apoptosis. Alternative lengthening of telomeres (ALT) is found in a subset of malignant brain tumors with poor outcomes. Here, we describe a model of juvenile zebr...

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Detalles Bibliográficos
Autores principales: Idilli, Aurora Irene, Cusanelli, Emilio, Pagani, Francesca, Berardinelli, Francesco, Bernabé, Manuel, Cayuela, María Luisa, Poliani, Pietro Luigi, Mione, Maria Caterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026139/
https://www.ncbi.nlm.nih.gov/pubmed/32117990
http://dx.doi.org/10.3389/fcell.2020.00065