Cargando…

On the relationship of first-episode psychosis to the amphetamine-sensitized state: a dopamine D(2/3) receptor agonist radioligand study

Schizophrenia is characterized by increased behavioral and neurochemical responses to dopamine-releasing drugs. This prompted the hypothesis of psychosis as a state of “endogenous” sensitization of the dopamine system although the exact basis of dopaminergic disturbances and the possible role of pre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weidenauer, Ana, Bauer, Martin, Sauerzopf, Ulrich, Bartova, Lucie, Nics, Lukas, Pfaff, Sarah, Philippe, Cecile, Berroterán-Infante, Neydher, Pichler, Verena, Meyer, Bernhard M., Rabl, Ulrich, Sezen, Patrick, Cumming, Paul, Stimpfl, Thomas, Sitte, Harald H., Lanzenberger, Rupert, Mossaheb, Nilufar, Zimprich, Alexander, Rusjan, Pablo, Dorffner, Georg, Mitterhauser, Markus, Hacker, Marcus, Pezawas, Lukas, Kasper, Siegfried, Wadsak, Wolfgang, Praschak-Rieder, Nicole, Willeit, Matthäus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026156/ https://www.ncbi.nlm.nih.gov/pubmed/32066718 http://dx.doi.org/10.1038/s41398-019-0681-5

Ejemplares similares

PM478. Imaging the effects of d-amphetamine in the human brain for modelling dopaminergic alterations in schizophrenia
por: Willeit, Matthäus, et al.
Publicado: (2016)

Toward the Optimization of (+)-[(11)C]PHNO Synthesis: Time Reduction and Process Validation
por: Pfaff, Sarah, et al.
Publicado: (2019)

PM476. d-Amphetamine-induced sensitization of the dopaminergic system in healthy human subjects: A [(11)C]-(+)-PHNO-PET study
por: Ana, Popovic, et al.
Publicado: (2016)

Making Sense of: Sensitization in Schizophrenia
por: Weidenauer, Ana, et al.
Publicado: (2016)

Disrupted relationship between blood glucose and brain dopamine D2/3 receptor binding in patients with first-episode schizophrenia
por: Sauerzopf, U., et al.
Publicado: (2021)

Association of dopamine D(2/3) receptor binding potential measured using PET and [(11)C]-(+)-PHNO with post-mortem DRD(2/3) gene expression in the human brain
por: Komorowski, Arkadiusz, et al.
Publicado: (2020)

Are reprogrammed cells a useful tool for studying dopamine dysfunction in psychotic disorders? A review of the current evidence
por: Sauerzopf, Ulrich, et al.
Publicado: (2016)

New approaches for the reliable in vitro assessment of binding affinity based on high-resolution real-time data acquisition of radioligand-receptor binding kinetics
por: Zeilinger, Markus, et al.
Publicado: (2017)

Binding Affinity of Some Endogenous and Synthetic TSPO Ligands Regarding the rs6971 Polymorphism
por: Berroterán-Infante, Neydher, et al.
Publicado: (2019)

Reliable set-up for in-loop (11)C-carboxylations using Grignard reactions for the preparation of [carbonyl-(11)C]WAY-100635 and [(11)C]-(+)-PHNO()
por: Rami-Mark, Christina, et al.
Publicado: (2013)

Radiosynthesis and first preclinical evaluation of the novel norepinephrine transporter pet-ligand [(11)C]ME@HAPTHI
por: Rami-Mark, Christina, et al.
Publicado: (2015)

Treatment of seasonal affective disorders
por: Praschak-Rieder, Nicole, et al.
Publicado: (2003)

Reduced default mode network suppression during a working memory task in remitted major depression
por: Bartova, Lucie, et al.
Publicado: (2015)

Preparation and First Preclinical Evaluation of [(18)F]FE@SNAP: A Potential PET Tracer for the Melanin-Concentrating Hormone Receptor-1 (MCHR1)
por: Philippe, Cécile, et al.
Publicado: (2013)

Biodistribution and dosimetry of the GluN2B-specific NMDA receptor PET radioligand (R)-[(11)C]Me-NB1
por: Rischka, Lucas, et al.
Publicado: (2022)

Platelet Serotonin Transporter Function Predicts Default-Mode Network Activity
por: Scharinger, Christian, et al.
Publicado: (2014)

Topologically Guided Prioritization of Candidate Gene Transcripts Coexpressed with the 5-HT(1A) Receptor by Combining In Vivo PET and Allen Human Brain Atlas Data
por: Unterholzner, Jakob, et al.
Publicado: (2020)

Parcellation of the Human Cerebral Cortex Based on Molecular Targets in the Serotonin System Quantified by Positron Emission Tomography In vivo
por: James, Gregory M, et al.
Publicado: (2019)

Case report: Interstitial pneumonitis after initiation of lamotrigine
por: Watzal, Victoria, et al.
Publicado: (2023)

Optimization of the Automated Synthesis of [(11)C]mHED—Administered and Apparent Molar Activities
por: Vraka, Chrysoula, et al.
Publicado: (2019)

DiGeorge syndrome: Relevance of psychiatric symptoms in undiagnosed adult patients
por: Kraus, Christoph, et al.
Publicado: (2018)

Attenuation Correction Approaches for Serotonin Transporter Quantification With PET/MRI
por: Rischka, Lucas, et al.
Publicado: (2019)

[(18)F]FE@SNAP—A new PET tracer for the melanin concentrating hormone receptor 1 (MCHR1): Microfluidic and vessel-based approaches
por: Philippe, Cécile, et al.
Publicado: (2012)

Neurobiological predictors for clinical trajectories in fully remitted depressed patients
por: Blank, Thomas S., et al.
Publicado: (2020)

Brain morphometry and connectivity differs between adolescent‐ and adult‐onset major depressive disorder
por: Blank, Thomas S., et al.
Publicado: (2022)

Development of a radiolabeled caninized anti-EGFR antibody for comparative oncology trials
por: Fazekas-Singer, Judit, et al.
Publicado: (2017)

[(18)F]FE@SUPPY: a suitable PET tracer for the adenosine A3 receptor? An in vivo study in rodents
por: Haeusler, Daniela, et al.
Publicado: (2015)

Assessment of Ketamine Binding of the Serotonin Transporter in Humans with Positron Emission Tomography
por: Spies, Marie, et al.
Publicado: (2017)

Prefrontal networks dynamically related to recovery from major depressive disorder: a longitudinal pharmacological fMRI study
por: Meyer, Bernhard M., et al.
Publicado: (2019)

Serotonin Transporter Binding in the Human Brain After Pharmacological Challenge Measured Using PET and PET/MR
por: Silberbauer, Leo R., et al.
Publicado: (2019)

Comparison of fully-automated radiosyntheses of [(11)C]erlotinib for preclinical and clinical use starting from in target produced [(11)C]CO(2) or [(11)C]CH(4)
por: Philippe, Cécile, et al.
Publicado: (2018)

Task-relevant brain networks identified with simultaneous PET/MR imaging of metabolism and connectivity
por: Hahn, Andreas, et al.
Publicado: (2017)

**-Postprandial pancreatic [(11)C]methionine uptake after pancreaticoduodenectomy mirrors basal beta cell function and insulin release
por: Steiner, Emanuel, et al.
Publicado: (2016)

Case report: Hyperactive delirium after a single dose of zolpidem administered additionally to psychopharmacotherapy including clozapine
por: Preiss, Maximilian, et al.
Publicado: (2023)

Sorbitol as a Polar Pharmacological Modifier to Enhance the Hydrophilicity of (99m)Tc-Tricarbonyl-Based Radiopharmaceuticals
por: Giammei, Carolina, et al.
Publicado: (2020)

Effects of bilateral sequential theta-burst stimulation on 5-HT(1A) receptors in the dorsolateral prefrontal cortex in treatment-resistant depression: a proof-of-concept trial
por: Murgaš, Matej, et al.
Publicado: (2023)

Preclinical In Vitro and In Vivo Evaluation of [(18)F]FE@SUPPY for Cancer PET Imaging: Limitations of a Xenograft Model for Colorectal Cancer
por: Balber, T., et al.
Publicado: (2018)

Psychotic-Like Experiences: A Challenge in Definition and Assessment
por: Hinterbuchinger, Barbara, et al.
Publicado: (2021)

[(18)F]FMeNER-D2: Reliable fully-automated synthesis for visualization of the norepinephrine transporter
por: Rami-Mark, Christina, et al.
Publicado: (2013)

Parameter evaluation and fully-automated radiosynthesis of [(11)C]harmine for imaging of MAO-A for clinical trials
por: Philippe, C., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_96r5u8qp12od6n4dnt252dq6e5