Intracerebroventricular infusion of donepezil prevents cardiac remodeling and improves the prognosis of chronic heart failure rats

Oral administration of donepezil, a centrally acting acetylcholinesterase inhibitor, improves the survival of rats with chronic heart failure (CHF). The mechanisms of cardioprotective effects of donepezil, however, remain totally unknown. To elucidate potential mechanisms, we examined whether centra...

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Detalles Bibliográficos
Autores principales: Li, Meihua, Zheng, Can, Kawada, Toru, Inagaki, Masashi, Uemura, Kazunori, Sugimachi, Masaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026239/
https://www.ncbi.nlm.nih.gov/pubmed/32066375
http://dx.doi.org/10.1186/s12576-020-00739-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026239/
https://www.ncbi.nlm.nih.gov/pubmed/32066375
http://dx.doi.org/10.1186/s12576-020-00739-0

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