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Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients

Current treatments for clear cell renal cell cancer (ccRCC) are insufficient because two-thirds of patients with metastases progress within two years. Here we report the identification and characterization of a cancer stem cell (CSC) population in ccRCC. CSCs are quantitatively correlated with tumor...

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Detalles Bibliográficos
Autores principales:	Fendler, Annika, Bauer, Daniel, Busch, Jonas, Jung, Klaus, Wulf-Goldenberg, Annika, Kunz, Severine, Song, Kun, Myszczyszyn, Adam, Elezkurtaj, Sefer, Erguen, Bettina, Jung, Simone, Chen, Wei, Birchmeier, Walter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026425/ https://www.ncbi.nlm.nih.gov/pubmed/32066735 http://dx.doi.org/10.1038/s41467-020-14700-7

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