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A polygenic predictor of treatment-resistant depression using whole exome sequencing and genome-wide genotyping

Treatment-resistant depression (TRD) occurs in ~30% of patients with major depressive disorder (MDD) but the genetics of TRD was previously poorly investigated. Whole exome sequencing and genome-wide genotyping were available in 1209 MDD patients after quality control. Antidepressant response was co...

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Detalles Bibliográficos
Autores principales: Fabbri, Chiara, Kasper, Siegfried, Kautzky, Alexander, Zohar, Joseph, Souery, Daniel, Montgomery, Stuart, Albani, Diego, Forloni, Gianluigi, Ferentinos, Panagiotis, Rujescu, Dan, Mendlewicz, Julien, Uher, Rudolf, Lewis, Cathryn M., Serretti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026437/
https://www.ncbi.nlm.nih.gov/pubmed/32066715
http://dx.doi.org/10.1038/s41398-020-0738-5