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PDCD4 controls the G1/S-phase transition in a telomerase-immortalized epithelial cell line and affects the expression level and translation of multiple mRNAs
PDCD4, the protein encoded by the tumor suppressor gene PDCD4 (programmed cell death 4) has been implicated in the control of cellular transcription and translation by modulating the activity of specific transcription factors and suppressing the translation of mRNAs with structured 5′-UTRs. Most stu...
Autores principales: | Haas, Astrid, Nilges, Benedikt S., Leidel, Sebastian A., Klempnauer, Karl-Heinz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026441/ https://www.ncbi.nlm.nih.gov/pubmed/32066800 http://dx.doi.org/10.1038/s41598-020-59678-w |
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