Identification and characterization of occult human-specific LINE-1 insertions using long-read sequencing technology

Long Interspersed Element-1 (LINE-1) retrotransposition contributes to inter- and intra-individual genetic variation and occasionally can lead to human genetic disorders. Various strategies have been developed to identify human-specific LINE-1 (L1Hs) insertions from short-read whole genome sequencin...

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Detalles Bibliográficos
Autores principales: Zhou, Weichen, Emery, Sarah B, Flasch, Diane A, Wang, Yifan, Kwan, Kenneth Y, Kidd, Jeffrey M, Moran, John V, Mills, Ryan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026601/
https://www.ncbi.nlm.nih.gov/pubmed/31853540
http://dx.doi.org/10.1093/nar/gkz1173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026601/
https://www.ncbi.nlm.nih.gov/pubmed/31853540
http://dx.doi.org/10.1093/nar/gkz1173

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