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Protect-seq: genome-wide profiling of nuclease inaccessible domains reveals physical properties of chromatin
In metazoan cell nuclei, heterochromatin constitutes large chromatin domains that are in close contact with the nuclear lamina. These heterochromatin/lamina-associated domains (LADs) domains are difficult to profile and warrants a simpler and direct method. Here we report a new method, Protect-seq,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026637/ https://www.ncbi.nlm.nih.gov/pubmed/31819993 http://dx.doi.org/10.1093/nar/gkz1150 |