Cargando…

Secondary nucleotide messenger c-di-GMP exerts a global control on natural product biosynthesis in streptomycetes

Cyclic dimeric 3′-5′ guanosine monophosphate, c-di-GMP, is a ubiquitous second messenger controlling diverse cellular processes in bacteria. In streptomycetes, c-di-GMP plays a crucial role in a complex morphological differentiation by modulating an activity of the pleiotropic regulator BldD. Here w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Makitrynskyy, Roman, Tsypik, Olga, Nuzzo, Desirèe, Paululat, Thomas, Zechel, David L, Bechthold, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Synthetic Biology and Bioengineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026642/ https://www.ncbi.nlm.nih.gov/pubmed/31956908 http://dx.doi.org/10.1093/nar/gkz1220

Ejemplares similares

Cyclic di-GMP cyclase SSFG_02181 from Streptomyces ghanaensis ATCC14672 regulates antibiotic biosynthesis and morphological differentiation in streptomycetes
por: Nuzzo, Desirèe, et al.
Publicado: (2020)

Identification and Characterization of Four c-di-GMP-Metabolizing Enzymes from Streptomyces ghanaensis ATCC14672 Involved in the Regulation of Morphogenesis and Moenomycin A Biosynthesis
por: Nuzzo, Desirèe, et al.
Publicado: (2021)

Regulatory Control of Rishirilide(s) Biosynthesis in Streptomyces bottropensis
por: Tsypik, Olga, et al.
Publicado: (2021)

Genetic Engineering of Streptomyces ghanaensis ATCC14672 for Improved Production of Moenomycins
por: Makitrynskyy, Roman, et al.
Publicado: (2021)

Bacterial Rotary Export ATPases Are Allosterically Regulated by the Nucleotide Second Messenger Cyclic-di-GMP
por: Trampari, Eleftheria, et al.
Publicado: (2015)

Parallelized gene cluster editing illuminates mechanisms of epoxyketone proteasome inhibitor biosynthesis
por: Huang, Chuan, et al.
Publicado: (2023)

Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin
por: Makitrynskyy, Roman, et al.
Publicado: (2013)

A general approach to high-yield biosynthesis of chimeric RNAs bearing various types of functional small RNAs for broad applications
por: Chen, Qiu-Xia, et al.
Publicado: (2015)

Integration of the Second Messenger c-di-GMP into the Chemotactic Signaling Pathway
por: Russell, Matthew H., et al.
Publicado: (2013)

Sensing the Messenger: Potential Roles of Cyclic-di-GMP in Rickettsial Pathogenesis
por: Narra, Hema P., et al.
Publicado: (2022)

Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP
por: Schumacher, Maria A., et al.
Publicado: (2022)

Biosynthesis of Rishirilide B
por: Schwarzer, Philipp, et al.
Publicado: (2018)

Control of light-dependent behaviour in cyanobacteria by the second messenger cyclic di-GMP
por: Enomoto, Gen, et al.
Publicado: (2023)

SimReg1 is a master switch for biosynthesis and export of simocyclinone D8 and its precursors
por: Horbal, Liliya, et al.
Publicado: (2012)

Locked and proteolysis-based transcription activator-like effector (TALE) regulation
por: Lonzarić, Jan, et al.
Publicado: (2016)

Intercepting second-messenger signaling by rationally designed peptides sequestering c-di-GMP
por: Hee, Chee-Seng, et al.
Publicado: (2020)

Post-translational environmental switch of RadA activity by extein–intein interactions in protein splicing
por: Topilina, Natalya I., et al.
Publicado: (2015)

Binding of the transcription activator-like effector augments transcriptional regulation by another transcription factor
por: Leben, Katja, et al.
Publicado: (2022)

Coupling of the engineered DNA “mutator” to a biosensor as a new paradigm for activation of silent biosynthetic gene clusters in Streptomyces
por: Sekurova, Olga N, et al.
Publicado: (2021)

Robust counterselection and advanced λRed recombineering enable markerless chromosomal integration of large heterologous constructs
por: Bubnov, Dmitrii M, et al.
Publicado: (2022)

Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA
por: Shebanova, Regina, et al.
Publicado: (2021)

Role of GntR Family Regulatory Gene SCO1678 in Gluconate Metabolism in Streptomyces coelicolor M145
por: Tsypik, Olga, et al.
Publicado: (2017)

The Multiple Regulatory Relationship Between RNA-Chaperone Hfq and the Second Messenger c-di-GMP
por: Fu, Yang, et al.
Publicado: (2021)

StreptomeDB 2.0—an extended resource of natural products produced by streptomycetes
por: Klementz, Dennis, et al.
Publicado: (2016)

Roles of the second messenger c‐di‐GMP in bacteria: Focusing on the topics of flagellar regulation and Vibrio spp.
por: Homma, Michio, et al.
Publicado: (2022)

A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP
por: McWhirter, Sarah M., et al.
Publicado: (2009)

Early Steps in the Biosynthetic Pathway of Rishirilide B
por: Schwarzer, Philipp, et al.
Publicado: (2020)

A universal strategy for regulating mRNA translation in prokaryotic and eukaryotic cells
por: Cao, Jicong, et al.
Publicado: (2015)

Selective inhibition of miR-21 by phage display screened peptide
por: Bose, Debojit, et al.
Publicado: (2015)

A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture
por: O'Geen, Henriette, et al.
Publicado: (2015)

De novo design of heat-repressible RNA thermosensors in E. coli
por: Hoynes-O'Connor, Allison, et al.
Publicado: (2015)

A predictive biophysical model of translational coupling to coordinate and control protein expression in bacterial operons
por: Tian, Tian, et al.
Publicado: (2015)

Tight regulation of plant immune responses by combining promoter and suicide exon elements
por: Gonzalez, Tania L., et al.
Publicado: (2015)

A fungicide-responsive kinase as a tool for synthetic cell fate regulation
por: Furukawa, Kentaro, et al.
Publicado: (2015)

Synthetic biosensors for precise gene control and real-time monitoring of metabolites
por: Rogers, Jameson K., et al.
Publicado: (2015)

Selection-free gene repair after adenoviral vector transduction of designer nucleases: rescue of dystrophin synthesis in DMD muscle cell populations
por: Maggio, Ignazio, et al.
Publicado: (2016)

Dealing with the genetic load in bacterial synthetic biology circuits: convergences with the Ohm's law
por: Carbonell-Ballestero, M., et al.
Publicado: (2016)

Algorithmic co-optimization of genetic constructs and growth conditions: application to 6-ACA, a potential nylon-6 precursor
por: Zhou, Hui, et al.
Publicado: (2015)

Reassignment of a rare sense codon to a non-canonical amino acid in Escherichia coli
por: Mukai, Takahito, et al.
Publicado: (2015)

Probing the active site tryptophan of Staphylococcus aureus thioredoxin with an analog
por: Englert, Markus, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_gan526r2ug6qgsqkdotip3odoe