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Divalent cations promote TALE DNA-binding specificity

Recent advances in gene editing have been enabled by programmable nucleases such as transcription activator-like effector nucleases (TALENs) and CRISPR–Cas9. However, several open questions remain regarding the molecular machinery in these systems, including fundamental search and binding behavior a...

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Detalles Bibliográficos
Autores principales:	Cuculis, Luke, Zhao, Chuankai, Abil, Zhanar, Zhao, Huimin, Shukla, Diwakar, Schroeder, Charles M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026652/ https://www.ncbi.nlm.nih.gov/pubmed/31863586 http://dx.doi.org/10.1093/nar/gkz1174

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