Cargando…
A dual role of dLsd1 in oogenesis: regulating developmental genes and repressing transposons
The histone demethylase LSD1 is a key chromatin regulator that is often deregulated in cancer. Its ortholog, dLsd1 plays a crucial role in Drosophila oogenesis; however, our knowledge of dLsd1 function is insufficient to explain its role in the ovary. Here, we have performed genome-wide analysis of...
Autores principales: | Lepesant, Julie M J, Iampietro, Carole, Galeota, Eugenia, Augé, Benoit, Aguirrenbengoa, Marion, Mercé, Clemèntine, Chaubet, Camille, Rocher, Vincent, Haenlin, Marc, Waltzer, Lucas, Pelizzola, Mattia, Di Stefano, Luisa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026653/ https://www.ncbi.nlm.nih.gov/pubmed/31799607 http://dx.doi.org/10.1093/nar/gkz1142 |
Ejemplares similares
-
Targeted DNA oxidation by LSD1–SMAD2/3 primes TGF-β1/ EMT genes for activation or repression
por: Pezone, Antonio, et al.
Publicado: (2020) -
LSD1 prevents aberrant heterochromatin formation in Neurospora crassa
por: Storck, William K, et al.
Publicado: (2020) -
LSD1 mediates metabolic reprogramming by glucocorticoids during myogenic differentiation
por: Anan, Kotaro, et al.
Publicado: (2018) -
LSD1 cooperates with CTIP2 to promote HIV-1 transcriptional silencing
por: Le Douce, Valentin, et al.
Publicado: (2012) -
Extranucleosomal DNA enhances the activity of the LSD1/CoREST histone demethylase complex
por: Kim, Sang-Ah, et al.
Publicado: (2015)