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Dynamic changes in intron retention are tightly associated with regulation of splicing factors and proliferative activity during B-cell development

Intron retention (IR) has been proposed to modulate the delay between transcription and translation. Here, we provide an exhaustive characterization of IR in differentiated white blood cells from both the myeloid and lymphoid lineage where we observed highest levels of IR in monocytes and B-cells, i...

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Detalles Bibliográficos
Autores principales: Ullrich, Sebastian, Guigó, Roderic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026658/
https://www.ncbi.nlm.nih.gov/pubmed/31879760
http://dx.doi.org/10.1093/nar/gkz1180