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Dynamic changes in intron retention are tightly associated with regulation of splicing factors and proliferative activity during B-cell development
Intron retention (IR) has been proposed to modulate the delay between transcription and translation. Here, we provide an exhaustive characterization of IR in differentiated white blood cells from both the myeloid and lymphoid lineage where we observed highest levels of IR in monocytes and B-cells, i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026658/ https://www.ncbi.nlm.nih.gov/pubmed/31879760 http://dx.doi.org/10.1093/nar/gkz1180 |