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IRSp53 Deletion in Glutamatergic and GABAergic Neurons and in Male and Female Mice Leads to Distinct Electrophysiological and Behavioral Phenotypes

IRSp53 (also known as BAIAP2) is an abundant excitatory postsynaptic scaffolding protein implicated in autism spectrum disorders (ASD), schizophrenia, and attention-deficit/hyperactivity disorder (ADHD). IRSp53 is expressed in different cell types across different brain regions, although it remains...

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Detalles Bibliográficos
Autores principales: Kim, Yangsik, Noh, Young Woo, Kim, Kyungdeok, Yang, Esther, Kim, Hyun, Kim, Eunjoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026675/
https://www.ncbi.nlm.nih.gov/pubmed/32116566
http://dx.doi.org/10.3389/fncel.2020.00023