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Indoleamine-2,3-Dioxygenase Mediates Emotional Deficits by the Kynurenine/Tryptophan Pathway in the Ethanol Addiction/Withdrawal Mouse Model

OBJECTIVE: Our study was designed to investigate whether the indoleamine-2,3-dioxygenase (IDO)-mediated kynurenine/tryptophan (KYN/TRP) pathway participates in the development of emotional deficits from ethanol addiction/withdrawal mice. METHODS: The expression of proinflammatory factors, including...

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Detalles Bibliográficos
Autores principales:	Jiang, Xi, Lin, Qian, Xu, Lexing, Chen, Ziwei, Yan, Qizhi, Chen, Lei, Yu, Xuefeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026684/ https://www.ncbi.nlm.nih.gov/pubmed/32116558 http://dx.doi.org/10.3389/fncel.2020.00011

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