Flies from a tertiary hospital in Rwanda carry multidrug-resistant Gram-negative pathogens including extended-spectrum beta-lactamase-producing E. coli sequence type 131

Multidrug-resistant gram-negative (MRGN) bacteria are a serious threat to global health. We used genomics to study MRGN obtained from houseflies in a tertiary Rwandan hospital. Our analysis revealed a high abundance of different MRGN including E. coli pathogenic lineage ST131 suggesting the importan...

Descripción completa

Detalles Bibliográficos
Autores principales: Heiden, Stefan E., Kurz, Mathis S. E., Bohnert, Jürgen, Bayingana, Claude, Ndoli, Jules M., Sendegeya, Augustin, Gahutu, Jean Bosco, Eger, Elias, Mockenhaupt, Frank P., Schaufler, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026959/
https://www.ncbi.nlm.nih.gov/pubmed/32066506
http://dx.doi.org/10.1186/s13756-020-0696-y
_version_ 1783498767932063744
author Heiden, Stefan E.
Kurz, Mathis S. E.
Bohnert, Jürgen
Bayingana, Claude
Ndoli, Jules M.
Sendegeya, Augustin
Gahutu, Jean Bosco
Eger, Elias
Mockenhaupt, Frank P.
Schaufler, Katharina
author_facet Heiden, Stefan E.
Kurz, Mathis S. E.
Bohnert, Jürgen
Bayingana, Claude
Ndoli, Jules M.
Sendegeya, Augustin
Gahutu, Jean Bosco
Eger, Elias
Mockenhaupt, Frank P.
Schaufler, Katharina
author_sort Heiden, Stefan E.
collection PubMed
description Multidrug-resistant gram-negative (MRGN) bacteria are a serious threat to global health. We used genomics to study MRGN obtained from houseflies in a tertiary Rwandan hospital. Our analysis revealed a high abundance of different MRGN including E. coli pathogenic lineage ST131 suggesting the important role of flies in disseminating highly virulent pathogens in clinical settings and beyond.
format Online
Article
Text
id pubmed-7026959
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-70269592020-02-24 Flies from a tertiary hospital in Rwanda carry multidrug-resistant Gram-negative pathogens including extended-spectrum beta-lactamase-producing E. coli sequence type 131 Heiden, Stefan E. Kurz, Mathis S. E. Bohnert, Jürgen Bayingana, Claude Ndoli, Jules M. Sendegeya, Augustin Gahutu, Jean Bosco Eger, Elias Mockenhaupt, Frank P. Schaufler, Katharina Antimicrob Resist Infect Control Short Report Multidrug-resistant gram-negative (MRGN) bacteria are a serious threat to global health. We used genomics to study MRGN obtained from houseflies in a tertiary Rwandan hospital. Our analysis revealed a high abundance of different MRGN including E. coli pathogenic lineage ST131 suggesting the important role of flies in disseminating highly virulent pathogens in clinical settings and beyond. BioMed Central 2020-02-17 /pmc/articles/PMC7026959/ /pubmed/32066506 http://dx.doi.org/10.1186/s13756-020-0696-y Text en © The Author(s). 2020 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Short Report
Heiden, Stefan E.
Kurz, Mathis S. E.
Bohnert, Jürgen
Bayingana, Claude
Ndoli, Jules M.
Sendegeya, Augustin
Gahutu, Jean Bosco
Eger, Elias
Mockenhaupt, Frank P.
Schaufler, Katharina
Flies from a tertiary hospital in Rwanda carry multidrug-resistant Gram-negative pathogens including extended-spectrum beta-lactamase-producing E. coli sequence type 131
title Flies from a tertiary hospital in Rwanda carry multidrug-resistant Gram-negative pathogens including extended-spectrum beta-lactamase-producing E. coli sequence type 131
title_full Flies from a tertiary hospital in Rwanda carry multidrug-resistant Gram-negative pathogens including extended-spectrum beta-lactamase-producing E. coli sequence type 131
title_fullStr Flies from a tertiary hospital in Rwanda carry multidrug-resistant Gram-negative pathogens including extended-spectrum beta-lactamase-producing E. coli sequence type 131
title_full_unstemmed Flies from a tertiary hospital in Rwanda carry multidrug-resistant Gram-negative pathogens including extended-spectrum beta-lactamase-producing E. coli sequence type 131
title_short Flies from a tertiary hospital in Rwanda carry multidrug-resistant Gram-negative pathogens including extended-spectrum beta-lactamase-producing E. coli sequence type 131
title_sort flies from a tertiary hospital in rwanda carry multidrug-resistant gram-negative pathogens including extended-spectrum beta-lactamase-producing e. coli sequence type 131
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026959/
https://www.ncbi.nlm.nih.gov/pubmed/32066506
http://dx.doi.org/10.1186/s13756-020-0696-y
work_keys_str_mv AT heidenstefane fliesfromatertiaryhospitalinrwandacarrymultidrugresistantgramnegativepathogensincludingextendedspectrumbetalactamaseproducingecolisequencetype131
AT kurzmathisse fliesfromatertiaryhospitalinrwandacarrymultidrugresistantgramnegativepathogensincludingextendedspectrumbetalactamaseproducingecolisequencetype131
AT bohnertjurgen fliesfromatertiaryhospitalinrwandacarrymultidrugresistantgramnegativepathogensincludingextendedspectrumbetalactamaseproducingecolisequencetype131
AT bayinganaclaude fliesfromatertiaryhospitalinrwandacarrymultidrugresistantgramnegativepathogensincludingextendedspectrumbetalactamaseproducingecolisequencetype131
AT ndolijulesm fliesfromatertiaryhospitalinrwandacarrymultidrugresistantgramnegativepathogensincludingextendedspectrumbetalactamaseproducingecolisequencetype131
AT sendegeyaaugustin fliesfromatertiaryhospitalinrwandacarrymultidrugresistantgramnegativepathogensincludingextendedspectrumbetalactamaseproducingecolisequencetype131
AT gahutujeanbosco fliesfromatertiaryhospitalinrwandacarrymultidrugresistantgramnegativepathogensincludingextendedspectrumbetalactamaseproducingecolisequencetype131
AT egerelias fliesfromatertiaryhospitalinrwandacarrymultidrugresistantgramnegativepathogensincludingextendedspectrumbetalactamaseproducingecolisequencetype131
AT mockenhauptfrankp fliesfromatertiaryhospitalinrwandacarrymultidrugresistantgramnegativepathogensincludingextendedspectrumbetalactamaseproducingecolisequencetype131
AT schauflerkatharina fliesfromatertiaryhospitalinrwandacarrymultidrugresistantgramnegativepathogensincludingextendedspectrumbetalactamaseproducingecolisequencetype131

Ejemplares similares