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Reduced hypertrophy in vitro after chondrogenic differentiation of adult human mesenchymal stem cells following adenoviral SOX9 gene delivery

BACKGROUND: Mesenchymal stem cell (MSC) based-treatments of cartilage injury are promising but impaired by high levels of hypertrophy after chondrogenic induction with several bone morphogenetic protein superfamily members (BMPs). As an alternative, this study investigates the chondrogenic induction...

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Detalles Bibliográficos
Autores principales:	Weissenberger, M., Weissenberger, M. H., Gilbert, F., Groll, J., Evans, C. H., Steinert, A. F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026978/ https://www.ncbi.nlm.nih.gov/pubmed/32066427 http://dx.doi.org/10.1186/s12891-020-3137-4

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