Analyses on clustering of the conserved residues at protein-RNA interfaces and its application in binding site identification

BACKGROUND: The maintenance of protein structural stability requires the cooperativity among spatially neighboring residues. Previous studies have shown that conserved residues tend to occur clustered together within enzyme active sites and protein-protein/DNA interfaces. It is possible that conserv...

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Detalles Bibliográficos
Autores principales: Yang, Zhen, Deng, Xueqing, Liu, Yang, Gong, Weikang, Li, Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027071/
https://www.ncbi.nlm.nih.gov/pubmed/32066366
http://dx.doi.org/10.1186/s12859-020-3398-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027071/
https://www.ncbi.nlm.nih.gov/pubmed/32066366
http://dx.doi.org/10.1186/s12859-020-3398-9

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