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The autocrine CXCR4/CXCL12 axis contributes to lung fibrosis through modulation of lung fibroblast activity

The C-X-C Motif Chemokine Receptor 4/C-X-C Motif Chemokine Ligand 12 (CXCR4/CXCL12) axis has been implicated in the pathogenesis of pulmonary fibrosis. However, the mechanisms governing this remain to be determined. The current study demonstrated that human lung fibroblasts (HLFs) exhibit high CXCL1...

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Detalles Bibliográficos
Autores principales: Li, Fei, Xu, Xuefeng, Geng, Jing, Wan, Xuan, Dai, Huaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027131/
https://www.ncbi.nlm.nih.gov/pubmed/32104240
http://dx.doi.org/10.3892/etm.2020.8433