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Minicircle DNA vector expressing interferon-lambda-3 inhibits hepatitis B virus replication and expression in hepatocyte-derived cell line

BACKGROUND: Interferon-alpha (IFNα) is a first-line treatment option for chronic hepatitis B virus (HBV) infection, but the severe systemic side-effects limited its clinical application. Interferon-lambda (IFNλ) with comparable antiviral activity and less toxic side-effects is thought to be a good a...

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Detalles Bibliográficos
Autores principales:	Guo, Xiaoyan, Chen, Dianke, Cai, Qingxian, Huang, Zhanlian, Xu, Wenxiong, Peng, Liang, Chen, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027252/ https://www.ncbi.nlm.nih.gov/pubmed/32070272 http://dx.doi.org/10.1186/s12860-020-00250-9

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