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Zerumbone ameliorates behavioral impairments and neuropathology in transgenic APP/PS1 mice by suppressing MAPK signaling

BACKGROUND: Alzheimer’s disease (AD) is a major clinical problem, but there is a distinct lack of effective therapeutic drugs for this disease. We investigated the potential therapeutic effects of zerumbone, a subtropical ginger sesquiterpene, in transgenic APP/PS1 mice, rodent models of AD which ex...

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Detalles Bibliográficos
Autores principales:	Li, Lei, Wu, Xiang-Hui, Zhao, Xiao-Jing, Xu, Lu, Pan, Cai-Long, Zhang, Zhi-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027354/ https://www.ncbi.nlm.nih.gov/pubmed/32066466 http://dx.doi.org/10.1186/s12974-020-01744-1

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