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Genetic Code Expansion Facilitates Position‐Selective Labeling of RNA for Biophysical Studies

Nature relies on reading and synthesizing the genetic code with high fidelity. Nucleic acid building blocks that are orthogonal to the canonical A‐T and G‐C base‐pairs are therefore uniquely suitable to facilitate position‐specific labeling of nucleic acids. Here, we employ the orthogonal kappa‐xant...

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Detalles Bibliográficos
Autores principales: Hegelein, Andreas, Müller, Diana, Größl, Sylvester, Göbel, Michael, Hengesbach, Martin, Schwalbe, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027469/
https://www.ncbi.nlm.nih.gov/pubmed/31692134
http://dx.doi.org/10.1002/chem.201904623