Neuroimmune interactions in chronic itch of atopic dermatitis

Itch is a defining symptom of atopic dermatitis. Crosstalk between keratinocytes, the immune system and non‐histaminergic sensory nerves is responsible for the pathophysiology of chronic itch in atopic dermatitis. An expanding understanding of the contribution of the nervous system and its interacti...

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Detalles Bibliográficos
Autores principales: Yosipovitch, G., Berger, T., Fassett, M.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027518/
https://www.ncbi.nlm.nih.gov/pubmed/31566796
http://dx.doi.org/10.1111/jdv.15973
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author Yosipovitch, G.
Berger, T.
Fassett, M.S.
author_facet Yosipovitch, G.
Berger, T.
Fassett, M.S.
author_sort Yosipovitch, G.
collection PubMed
description Itch is a defining symptom of atopic dermatitis. Crosstalk between keratinocytes, the immune system and non‐histaminergic sensory nerves is responsible for the pathophysiology of chronic itch in atopic dermatitis. An expanding understanding of the contribution of the nervous system and its interaction with immune pathways in atopic itch are helping to identify new therapeutic strategies.
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spelling pubmed-70275182020-02-24 Neuroimmune interactions in chronic itch of atopic dermatitis Yosipovitch, G. Berger, T. Fassett, M.S. J Eur Acad Dermatol Venereol Review Articles Itch is a defining symptom of atopic dermatitis. Crosstalk between keratinocytes, the immune system and non‐histaminergic sensory nerves is responsible for the pathophysiology of chronic itch in atopic dermatitis. An expanding understanding of the contribution of the nervous system and its interaction with immune pathways in atopic itch are helping to identify new therapeutic strategies. John Wiley and Sons Inc. 2019-11-12 2020-02 /pmc/articles/PMC7027518/ /pubmed/31566796 http://dx.doi.org/10.1111/jdv.15973 Text en © 2019 The Authors. Journal of the European Academy of Dermatology and Venereology published by John Wiley & Sons Ltd on behalf of European Academy of Dermatology and Venereology. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Review Articles
Yosipovitch, G.
Berger, T.
Fassett, M.S.
Neuroimmune interactions in chronic itch of atopic dermatitis
title Neuroimmune interactions in chronic itch of atopic dermatitis
title_full Neuroimmune interactions in chronic itch of atopic dermatitis
title_fullStr Neuroimmune interactions in chronic itch of atopic dermatitis
title_full_unstemmed Neuroimmune interactions in chronic itch of atopic dermatitis
title_short Neuroimmune interactions in chronic itch of atopic dermatitis
title_sort neuroimmune interactions in chronic itch of atopic dermatitis
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027518/
https://www.ncbi.nlm.nih.gov/pubmed/31566796
http://dx.doi.org/10.1111/jdv.15973
work_keys_str_mv AT yosipovitchg neuroimmuneinteractionsinchronicitchofatopicdermatitis
AT bergert neuroimmuneinteractionsinchronicitchofatopicdermatitis
AT fassettms neuroimmuneinteractionsinchronicitchofatopicdermatitis

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