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Glucocorticoids rapidly activate cAMP production via G(αs) to initiate non‐genomic signaling that contributes to one‐third of their canonical genomic effects

Glucocorticoids are widely used for the suppression of inflammation, but evidence is growing that they can have rapid, non‐genomic actions that have been unappreciated. Diverse cell signaling effects have been reported for glucocorticoids, leading us to hypothesize that glucocorticoids alone can swi...

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Detalles Bibliográficos
Autores principales: Nuñez, Francisco J., Johnstone, Timothy B., Corpuz, Maia L., Kazarian, Austin G., Mohajer, Nicole N., Tliba, Omar, Panettieri, Reynold A., Koziol‐White, Cynthia, Roosan, Moom R., Ostrom, Rennolds S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027561/
https://www.ncbi.nlm.nih.gov/pubmed/31908022
http://dx.doi.org/10.1096/fj.201902521R