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A Fluorescence‐Based Assay for Screening β‐Lactams Targeting the Mycobacterium tuberculosis Transpeptidase Ldt(Mt2)

Mycobacterium tuberculosis l,d‐transpeptidases (Ldts), which are involved in cell‐wall biosynthesis, have emerged as promising targets for the treatment of tuberculosis. However, an efficient method for testing inhibition of these enzymes is not currently available. We present a fluorescence‐based a...

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Detalles Bibliográficos
Autores principales:	de Munnik, Mariska, Lohans, Christopher T., Langley, Gareth W., Bon, Corentin, Brem, Jürgen, Schofield, Christopher J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028133/ https://www.ncbi.nlm.nih.gov/pubmed/31322798 http://dx.doi.org/10.1002/cbic.201900379

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