3-Bromopyruvate alleviates the development of monocrotaline-induced rat pulmonary arterial hypertension by decreasing aerobic glycolysis, inducing apoptosis, and suppressing inflammation

BACKGROUND: Pulmonary arterial hypertension (PH) is a progressive disease with limited therapeutic options, ultimately leading to right heart failure and death. Recent findings indicate the role of the Warburg effect (aerobic glycolysis) in the development of PH. However, the effect of the glycolysi...

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Detalles Bibliográficos
Autores principales: Liu, Jie, Wang, Wang, Wang, Lei, Qi, Xian-Mei, Sha, Yu-Hui, Yang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028200/
https://www.ncbi.nlm.nih.gov/pubmed/31923104
http://dx.doi.org/10.1097/CM9.0000000000000577

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