Genetic variation in Interleukin-32 influence the immune response against New World Leishmania species and susceptibility to American Tegumentary Leishmaniasis

Interleukin-32 is a novel inflammatory mediator that has been described to be important in the immunopathogenesis and control of infections caused by Leishmania parasites. By performing experiments with primary human cells in vitro, we demonstrate that the expression of IL-32 isoforms is dependent o...

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Detalles Bibliográficos
Autores principales: dos Santos, Jéssica Cristina, Leite Quixabeira, Valéria Bernadete, Teodoro Silva, Muriel Vilela, Damen, Michelle S. M. A., Schraa, Kiki, Jaeger, Martin, Oosting, Marije, Keating, Samuel T., Dorta, Miriam Leandro, Alves Pinto, Sebastião, Bugalho Duarte, Fernanda, de Araújo Pereira, Ledice Inácia, Netea, Mihai G., Ribeiro-Dias, Fátima, Joosten, Leo A. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028298/
https://www.ncbi.nlm.nih.gov/pubmed/32023240
http://dx.doi.org/10.1371/journal.pntd.0008029

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