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Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes

The nucleus of oocytes (germinal vesicle) is unusually large and its nuclear envelope (NE) is densely packed with nuclear pore complexes (NPCs) that are stockpiled for embryonic development. We showed that breakdown of this specialized NE is mediated by an Arp2/3-nucleated F-actin ‘shell’ in starfis...

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Detalles Bibliográficos
Autores principales: Wesolowska, Natalia, Avilov, Ivan, Machado, Pedro, Geiss, Celina, Kondo, Hiroshi, Mori, Masashi, Lenart, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028370/
https://www.ncbi.nlm.nih.gov/pubmed/31989921
http://dx.doi.org/10.7554/eLife.49774